Herceptin (Trasuzumab) is a humanized monoclonal antibody used in cancer treatment for Human Epidermal Growth Factor Receptor 2 (HER2) over-expressing tumors. In the case of these tumors, Herceptin binds to and inhibits tumor growth. Herceptin can also be labeled with various toxins to enhance tumor suppression. Studies have also found that Herceptin targets gastric cancer stem cells characterized by CD90 phenotype.
This test kit was developed for the measurement of Herceptin (Trastuzumab). However, all the ADC (Antibody Drug Conjugate) drug using Herceptin as carrier antibody can be measured with this assay. These ADC drugs include Trastuzumab emtansine (KADCYLA), Trastuzumab deruxtecan (ENHERTU), etc.
For research use only. Not for use in diagnostics procedures.