Human VDBP (GC Globulin) ELISA Kit


This test kit is intended for use in the quantitative determination of free (not actin complex bound) Vitamin D Binding Protein (VDBP, also known as GC Globulin) in human serum and plasma.

​​​​​​​This kit is for in vitro diagnostic use only.


Vitamin D-binding protein (DBP) is a 58 kDa circulating glycoprotein secreted by the liver. It binds about 85% to 90% of circulating 25- OH-D2/3 and 1,25-(OH)2-D3, regulates the bioavailability of active vitamin D, and transports them to target organs. There is only less than one percent 25-OH D2/3 is in the free form in the circulation. The full length DBP contains 476-amino acids, including a 16-amino acid signal sequence. Biologically, DBP may involve directly and indirectly in regulating bone metabolism.
Circulating DBP also binds to actin at 1:1 molecule ratio, while this protein complex is removed by kidney. In patient with trauma, sepsis or multiple organ failure, DBP concentration decreases. Urine DBP is reported to be a biomarker of major renal event in patient undergoing coronary angiography.


Catalog no. KT-896
Target Vitamin D Binding Protein
Species Human
Method Sandwich ELISA
Tests Per Kit 96 tests
Detection Colorimetric
Sensitivity / LLOD 0.0637 μg /mL
Dynamic Range 0 - 20.1 μg/mL
Total Incubation Time 1 hour, 20 minutes
Sample Type serum, plasma
Sample Volume 15 µL
Storage Temperature 2-8 °C
For in-vitro diagnostic use.