Your partner for human FGF-21 related research projects.
Many research of FGF-21 performed based on general FGF-21 test, which measures both intact FGF-21 and FGF-21 fragments. However, it is essential to study intact FGF-21, as well as FGF-21 fragments seperately, because
Human Intact FGF-21 (1-181) binds to β-Klotho and FGFR, initiating an intracellular signaling pathway that leads to various biological activities.
N-truncated and C-truncated FGF-21, while not biologically active themselves, may possess antagonistic functions by acting as receptor or protein binding agents. These truncated forms have the potential to interfere with normal FGF-21 signaling or disrupt interactions with other proteins.
Epitope Diagnostics offers following human FGF-21 tools for your scientific research and development.
KTR-879 Serolisa™ Human intact FGF-21(1-181) ELISA Kit
KTR-866 Serolisa™ Human ncFGF-21 ELISA Kit
KTR-873 Serolisa™ Human nFGF-21 ELISA Kit
KTR-874 Serolisa™ Human cFGF-21 ELISA Kit
30661 Anti-human FGF-21 (176-181), C-terminal Specific Antibody, Affinity purified
30618 Anti-human FGF-21 (1-6), N-terminal Specific Antibody, Affinity purified
Related literatures by using the above human intact FGF-21 ELISA: 1. Andrew L. Coppage, Kathryn R. Heard, Matthew T. DiMare, et al. Human FGF-21 Is a Substrate of Fibroblast Activation Protein March 10, 2016 https://doi.org/10.1371/journal.pone.0151269
2. Rashmi S, Modagan P, Silambanan S (2020): FGF-21 as a bone adiposity marker in osteoporosis, Ann Trop Med & Public Health; 23(S23): SP232371.
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Epitope Diagnostics Inc., is a certified medical device manufacture company located in San Diego, California, USA. We strive to offer the highest qulity tests for the use in professional laboratories.